Gastric Botox
An endoscopic procedure using botulinum toxin injections into the stomach to slow gastric emptying and reduce appetite.
Plain English
Patient-Friendly Explanation
Gastric Botox is a non-surgical weight loss procedure where botulinum toxin (Botox) is injected into the stomach wall through an endoscope — a thin, flexible tube passed through your mouth. The Botox relaxes the stomach muscles, slowing down how quickly food empties from your stomach, which helps you feel full longer and eat less. The effect lasts about 4 to 6 months.
Medical
Clinical Definition
Gastric botulinum toxin injection is an endoscopic procedure in which 200–300 units of botulinum toxin type A are injected into the gastric antrum, fundus, and body via oesophagogastroduodenoscopy. The toxin inhibits acetylcholine release at neuromuscular junctions, inducing reversible smooth muscle relaxation and delayed gastric emptying. Meta-analyses report mean total body weight loss of 5–10% at 6 months, though efficacy varies and the procedure remains investigational in several jurisdictions.
Key Insight
Why It Matters
Gastric Botox offers a temporary, repeatable option for patients who need modest weight loss but are not ready for permanent bariatric surgery. Dr Joseph Wang at Accord Medical can discuss whether this procedure fits your weight management goals and overall health profile.
Sources
Reviewed against standard medical references.
Medically reviewed by
Family Physician & Registered Acupuncturist, Accord Medical Clinic. MBBS (NUS), Graduate Diploma in Family Medicine (NUS), Graduate Diploma in Acupuncture (Singapore College of TCM).
Last reviewed: August 2026
This page is general health education, not medical advice. Whether any treatment is appropriate for you is a decision made in consultation after assessment.
