Duodenal-Jejunal Bypass Liner (EndoBarrier)
A removable intestinal sleeve placed by endoscopy that mimics gastric bypass hormone changes to reduce appetite and improve blood sugar.
Plain English
Patient-Friendly Explanation
A thin, flexible sleeve that is placed inside the first part of the small intestine during a short camera-guided procedure. It stops food from touching this part of the gut for up to a year, changing appetite and digestion hormones to help you feel full and lose weight.
Medical
Clinical Definition
An endoscopically implanted, impermeable fluoropolymer liner that lines the proximal duodenum and proximal jejunum, creating a mechanical barrier that prevents chyme from contacting the intestinal mucosa. This mimics the hormonal changes of Roux-en-Y gastric bypass, reducing glucose absorption and altering incretin secretion, which improves glycaemic control and induces weight loss. The device is removed endoscopically after up to 12 months.
Key Insight
Why It Matters
This offers a reversible, non-surgical option for patients who need more than medication but are not candidates for, or not ready to commit to, bariatric surgery. Dr. Joseph Wang can explain whether an endoscopic device like this fits your weight management plan.
Sources
Reviewed against standard medical references.
Medically reviewed by
Family Physician & Registered Acupuncturist, Accord Medical Clinic. MBBS (NUS), Graduate Diploma in Family Medicine (NUS), Graduate Diploma in Acupuncture (Singapore College of TCM).
Last reviewed: August 2026
This page is general health education, not medical advice. Whether any treatment is appropriate for you is a decision made in consultation after assessment.
