Sibutramine
A satiety-enhancing weight-loss drug withdrawn in 2010 due to increased heart and stroke risk.
Plain English
Patient-Friendly Explanation
An older weight-loss medicine that worked by making people feel full sooner. It was withdrawn from the market in 2010 because of safety concerns about heart and stroke risk.
Medical
Clinical Definition
A serotonin-norepinephrine reuptake inhibitor that reduced body weight by enhancing satiety and increasing energy expenditure. It was withdrawn from most markets, including Singapore and the European Union, in 2010 after the SCOUT trial found an increased risk of non-fatal myocardial infarction and stroke in patients with pre-existing cardiovascular disease.
Key Insight
Why It Matters
Sibutramine illustrates why medication safety monitoring is essential in weight management. Dr. Joseph Wang prescribes only evidence-based, currently approved treatments with proven safety profiles.
Sources
Reviewed against standard medical references.
Medically reviewed by
Family Physician & Registered Acupuncturist, Accord Medical Clinic. MBBS (NUS), Graduate Diploma in Family Medicine (NUS), Graduate Diploma in Acupuncture (Singapore College of TCM).
Last reviewed: August 2026
This page is general health education, not medical advice. Whether any treatment is appropriate for you is a decision made in consultation after assessment.
