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Hyperuricaemia and Obesity

Elevated blood uric acid is strongly linked to obesity and can lead to gout; weight loss helps lower uric acid levels naturally.

Plain English

Patient-Friendly Explanation

Hyperuricaemia means having too much uric acid in your blood — a condition strongly linked to excess body weight. High uric acid levels can lead to gout (painful joint inflammation) and kidney stones, but the good news is that weight loss can effectively lower uric acid levels.

Medical

Clinical Definition

Hyperuricaemia (serum uric acid above 6.8 mg/dL in men and 6.0 mg/dL in women) is bidirectionally associated with obesity through multiple mechanisms: obesity increases uric acid production via adipokine-mediated xanthine oxidase upregulation while reducing renal urate excretion through insulin resistance-induced sodium retention. Hyperuricaemia is an independent risk factor for hypertension, chronic kidney disease, and metabolic syndrome progression.

Key Insight

Why It Matters

Weight loss of as little as 5-10% can significantly lower uric acid levels, often reducing or eliminating the need for urate-lowering medications. At Accord Medical, Dr Joseph Wang can monitor your uric acid levels as part of a holistic weight management programme.

Sources

Reviewed against standard medical references.

Medically reviewed by

Dr Joseph Wang

Family Physician & Registered Acupuncturist, Accord Medical Clinic. MBBS (NUS), Graduate Diploma in Family Medicine (NUS), Graduate Diploma in Acupuncture (Singapore College of TCM).

Last reviewed: August 2026

This page is general health education, not medical advice. Whether any treatment is appropriate for you is a decision made in consultation after assessment.

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