Anorexigenic Signals
Anorexigenic signals are the body's natural stop-eating messages — chemical messengers that promote fullness and suppress appetite after eating.
Plain English
Patient-Friendly Explanation
Anorexigenic signals are your body's natural "stop eating" messages. These are chemical messengers that tell your brain you've had enough food, helping you feel full and satisfied after a meal.
Medical
Clinical Definition
Anorexigenic signals are neuroendocrine pathways that suppress appetite and promote satiety. Key mediators include leptin (from adipose tissue), peptide YY (PYY) and glucagon-like peptide-1 (GLP-1) from the gut, and alpha-melanocyte-stimulating hormone (α-MSH) in the hypothalamus. Impairment of anorexigenic signalling is a major contributor to obesity.
Key Insight
Why It Matters
GLP-1 receptor agonists work by amplifying anorexigenic signalling — essentially boosting your body's natural "fullness" messages. Dr Joseph Wang uses these insights to select the most effective treatment for Accord Medical patients.
Sources
Reviewed against standard medical references.
Medically reviewed by
Family Physician & Registered Acupuncturist, Accord Medical Clinic. MBBS (NUS), Graduate Diploma in Family Medicine (NUS), Graduate Diploma in Acupuncture (Singapore College of TCM).
Last reviewed: August 2026
This page is general health education, not medical advice. Whether any treatment is appropriate for you is a decision made in consultation after assessment.
