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Hormones
Ghrelin
The hunger hormone — stimulates appetite before meals.
PLAIN ENGLISH
Patient-Friendly Explanation
Ghrelin is your “hunger hormone.” Levels rise before meals and fall after eating. Some weight loss methods increase ghrelin, making you hungrier — which is why medical support helps.
MEDICAL
Clinical Definition
Ghrelin is a 28-amino acid peptide secreted primarily by gastric fundus cells. It acts on the arcuate nucleus to stimulate appetite. Levels increase during calorie restriction, contributing to weight regain.
KEY INSIGHT
Why It Matters
GLP-1 agonists suppress ghrelin secretion, providing dual appetite control. Understanding this mechanism helps patients appreciate why medication can be necessary.
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This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional for medical concerns. Accord Medical Clinic Singapore is an MOH-registered medical clinic in Singapore. Dr Joseph Wang (Family Physician) provides medical weight management consultations.