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Medications
CagriSema
CagriSema is an investigational combination injection of cagrilintide and semaglutide that targets multiple appetite pathways for enhanced weight loss.
PLAIN ENGLISH
Patient-Friendly Explanation
CagriSema is an investigational weight loss treatment that combines two medicines — cagrilintide and semaglutide — into a single weekly injection. Early studies show it may produce greater weight loss than either medicine alone by targeting multiple appetite pathways simultaneously.
MEDICAL
Clinical Definition
CagriSema is a fixed-dose combination of cagrilintide (a long-acting amylin analogue) and semaglutide (a GLP-1 receptor agonist) administered as a once-weekly subcutaneous injection. In the phase 2 REDEFINE 1 trial, CagriSema demonstrated superior weight loss compared to semaglutide monotherapy by combining amylin-mediated satiety and delayed gastric emptying with GLP-1-mediated appetite suppression.
KEY INSIGHT
Why It Matters
Combination therapies like CagriSema represent the next frontier in medical weight management. At Accord Medical, Dr Joseph Wang stays current with emerging treatments to offer patients the most advanced options available for sustainable weight loss.
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This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional for medical concerns. Accord Medical Clinic Singapore is an MOH-registered medical clinic in Singapore. Dr Joseph Wang (Family Physician) provides medical weight management consultations.