Menopause and Weight Gain
Weight gain driven by declining oestrogen during menopause — shifts fat storage to the abdomen, slows metabolism, and increases cardiometabolic risk.
Lipotoxicity
The damaging effects of excess fat accumulation in organs like the liver, pancreas, and muscles — a key mechanism linking obesity to diabetes and organ dysfunction.
Lipohypertrophy
Lipohypertrophy is abnormal fat accumulation at insulin injection sites that can interfere with diabetes management and complicate weight loss efforts.
Hypothalamic Obesity
Hypothalamic obesity is weight gain caused by damage to the hypothalamus, the brain centre for hunger control, leading to relentless appetite and metabolic disruption.
Obesity Hypoventilation Syndrome
A serious breathing disorder in people with severe obesity where excess weight restricts lung function.
Night Eating Syndrome
Night Eating Syndrome is a condition where a person consumes a large portion of daily calories after dinner or during the night, often with morning appetite loss.
Lipidema
Lipidema is a chronic condition causing painful, abnormal fat accumulation mainly in the legs and arms, often mistaken for simple obesity.
Depression and Obesity
Depression and obesity have a bidirectional relationship — each increases the risk and severity of the other, requiring integrated treatment.
Chronic Kidney Disease and Obesity
Chronic Kidney Disease (CKD) is gradual loss of kidney function, and obesity is a major risk factor — weight loss can help slow its progression.
Prader-Willi Syndrome
A rare genetic disorder causing constant extreme hunger, slow metabolism, and lifelong weight management challenges.