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Medications
Semaglutide
A GLP-1 receptor agonist medication used for weight management and type 2 diabetes.
PLAIN ENGLISH
Patient-Friendly Explanation
Semaglutide is a once-weekly injectable medication that helps you lose weight by making you feel fuller for longer and reducing your appetite. It mimics a natural hormone in your body called GLP-1. Your doctor at Accord Medical Clinic will assess if this treatment is suitable for you.
MEDICAL
Clinical Definition
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. It acts on GLP-1 receptors in the hypothalamus to reduce appetite, and in the gastrointestinal tract to slow gastric emptying. Approved by HSA for chronic weight management in Singapore.
KEY INSIGHT
Why It Matters
Clinical trials (STEP programme) demonstrated an average weight loss of 14.9% of initial body weight over 68 weeks when combined with lifestyle intervention. Understanding this medication helps patients make informed decisions about their weight management journey.
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This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional for medical concerns. Accord Medical Clinic Singapore is an MOH-registered medical clinic in Singapore. Dr Joseph Wang (Family Physician) provides medical weight management consultations.