Orexigenic Signals
Orexigenic signals are the body’s natural “eat more” messages — hormones and brain chemicals that drive hunger and food intake.
Metabolic Flexibility
Metabolic flexibility is the body’s ability to switch between burning carbohydrates and fats — poor flexibility is linked to weight gain and insulin resistance.
Energy Density
Energy density is the number of calories per gram of food — choosing lower-density foods helps you feel full while controlling calorie intake.
Adipogenesis
The biological process by which the body creates new fat cells from precursor cells, influencing energy storage and metabolism.
Appetite Regulation
The neuroendocrine system of hormones and brain signals that controls hunger and fullness, targeted by modern weight loss medications.
Lipolysis
The biological process of breaking down stored fat into usable energy, driven by a caloric deficit and regulated by hormones like insulin and adrenaline.
Adaptive Thermogenesis
The body’s metabolic defence mechanism that disproportionately slows energy expenditure during and after weight loss.
Adipokines
Bioactive signalling proteins secreted by fat cells that regulate metabolism, inflammation, and appetite throughout the body.
Resting Metabolic Rate (RMR)
Resting Metabolic Rate is the energy your body uses at complete rest — understanding it helps create personalised weight management plans.
Obesogenic Environment
An obesogenic environment is a setting that promotes weight gain through easy access to unhealthy food and barriers to physical activity.